Central alpha 1-adrenergic stimulation in relation to the behaviour stimulating effect of modafinil; studies with experimental animals.

@article{Duteil1990CentralA1,
  title={Central alpha 1-adrenergic stimulation in relation to the behaviour stimulating effect of modafinil; studies with experimental animals.},
  author={Jacques Duteil and Francis A. Rambert and J Pessonnier and Jean-François Hermant and R Gombert and E Assous},
  journal={European journal of pharmacology},
  year={1990},
  volume={180 1},
  pages={49-58}
}
Single administration of the new drug modafinil was followed by an increase in locomotor activity in mice and in nocturnal activity in monkeys. Stereotyped behaviour in mice and rats, and potentiation of amphetamine-induced stereotyped behaviour were not observed; however, at the highest dose used, a slight potentiation of apomorphine-induced stereotyped… CONTINUE READING