Central adiposity is associated with increased risk of esophageal inflammation, metaplasia, and adenocarcinoma: a systematic review and meta-analysis.

@article{Singh2013CentralAI,
  title={Central adiposity is associated with increased risk of esophageal inflammation, metaplasia, and adenocarcinoma: a systematic review and meta-analysis.},
  author={Siddharth Singh and Anamay N Sharma and Mohammad Hassan Murad and Navtej S. Buttar and Hashem B. El-Serag and D A Katzka and Prasad G Iyer},
  journal={Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association},
  year={2013},
  volume={11 11},
  pages={
          1399-1412.e7
        }
}
BACKGROUND & AIMS Central adiposity has been implicated as a risk factor for Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC), possibly promoting the progression from inflammation to metaplasia and neoplasia. We performed a systematic review and meta-analysis of studies to evaluate the association between central adiposity and erosive esophagitis (EE), BE, and EAC, specifically exploring body mass index (BMI)-independent and gastroesophageal reflux (GERD)-independent effects of… CONTINUE READING
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