Central Role of CD45RA- Foxp3hi Memory Regulatory T Cells in Clinical Kidney Transplantation Tolerance.

@article{Braza2015CentralRO,
  title={Central Role of CD45RA- Foxp3hi Memory Regulatory T Cells in Clinical Kidney Transplantation Tolerance.},
  author={F Braza and Emilie Dugast and I. R. Panov and Chlo{\'e} Paul and Katrin Vogt and Annaick Pallier and M{\'e}lanie Chesneau and Daniel Baron and Pierrick Gu{\'e}rif and Hong Lei and David-Axel Laplaud and Hans Dieter Volk and Nicolas Degauque and Magali Giral and J P Soulillou and B Sawitzki and Sophie Brouard},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2015},
  volume={26 8},
  pages={1795-805}
}
The role of Foxp3(+) regulatory T cells (Tregs) in operational tolerance remains elusive, as initial results revealed an increased frequency of this subset in tolerant patients but no functional differences compared with immunosuppressed recipients. In addition, recent studies of regulatory B cells strongly suggest that Tregs may not have a central role in kidney transplantation tolerance. However, recent investigations of the crucial role of Foxp3 demethylation in Treg function and the… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.
17 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Similar Papers

Loading similar papers…