Central Regulation of Metabolism by Protein Tyrosine Phosphatases

@inproceedings{Tsou2012CentralRO,
  title={Central Regulation of Metabolism by Protein Tyrosine Phosphatases},
  author={Ryan C. Tsou and Kendra K. Bence},
  booktitle={Front. Neurosci.},
  year={2012}
}
Protein tyrosine phosphatases (PTPs) are important regulators of intracellular signaling pathways via the dephosphorylation of phosphotyrosyl residues on various receptor and non-receptor substrates. The phosphorylation state of central nervous system (CNS) signaling components underlies the molecular mechanisms of a variety of physiological functions including the control of energy balance and glucose homeostasis. In this review, we summarize the current evidence implicating PTPs as central… CONTINUE READING
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