Central Gain Control in Tinnitus and Hyperacusis

  title={Central Gain Control in Tinnitus and Hyperacusis},
  author={Benjamin D. Auerbach and Paulo Rodrigues and Richard Salvi},
  booktitle={Front. Neurol.},
Sensorineural hearing loss induced by noise or ototoxic drug exposure reduces the neural activity transmitted from the cochlea to the central auditory system. Despite a reduced cochlear output, neural activity from more central auditory structures is paradoxically enhanced at suprathreshold intensities. This compensatory increase in the central auditory activity in response to the loss of sensory input is referred to as central gain enhancement. Enhanced central gain is hypothesized to be a… CONTINUE READING
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