Central Dogma Reversed

  title={Central Dogma Reversed},
  • Published 1970
  • Medicine
  • Nature

The Central Dogma of Information

Info-autopoiesis suggests that the authors' dreams for sentient artificial general intelligence and superintelligence are misguided and parallel the central dogma of molecular biology which states that ‘once (sequential) information has passed into protein it cannot get out again’.

Towards a deeper understanding of the human brain

Identifying the proteome variation in different parts of the body provides fundamental molecular details, enabling further findings and mapping of tissue specific proteins, and combining quantitativ and proteomics techniques helps to map the structure and function of these proteins.

60 years ago, Francis Crick changed the logic of biology

This essay explores the concepts Francis Crick developed in this influential lecture, including his prediction that the authors would study evolution by comparing sequences, which still frame how they understand life.

Theory of the Origin, Evolution, and Nature of Life

A theoretical framework that economically fits evidence accumulated from examinations of life and unifies the macrocosmic and microcosmic realms, validates predicted laws of nature, and solves the puzzle of the origin and evolution of cellular life in the universe.

Telomerase and retrotransposons: Reverse transcriptases that shaped genomes

“Two independent groups of investigators have found evidence of an enzyme… which synthesizes DNA from an RNA template. This discovery, if upheld, will have important implications… information

RNA in Brain Disease: No Longer Just "The Messenger in the Middle"

An overview of new research highlighting functions for RNA that far surpass the "messenger in the middle" role and that identify RNA molecules as important agents in the human brain in health and in disease states is presented.