Central Connectivity of Transient Receptor Potential Melastatin 8-Expressing Axons in the Brain Stem and Spinal Dorsal Horn

@inproceedings{Kim2014CentralCO,
  title={Central Connectivity of Transient Receptor Potential Melastatin 8-Expressing Axons in the Brain Stem and Spinal Dorsal Horn},
  author={Yun Sook Kim and Jun Hong Park and Su Jung Choi and Jin Young Bae and Dong Kuk Ahn and D D Mckemy and Yong Chul Bae},
  booktitle={PloS one},
  year={2014}
}
Transient receptor potential melastatin 8 (TRPM8) ion channels mediate the detection of noxious and innocuous cold and are expressed by primary sensory neurons, but little is known about the processing of the TRPM8-mediated cold information within the trigeminal sensory nuclei (TSN) and the spinal dorsal horn (DH). To address this issue, we characterized TRPM8-positive (+) neurons in the trigeminal ganglion and investigated the distribution of TRPM8+ axons and terminals, and their synaptic… CONTINUE READING

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