Central Canal Ependymal Cells Proliferate Extensively in Response to Traumatic Spinal Cord Injury but Not Demyelinating Lesions

@inproceedings{Lacroix2014CentralCE,
  title={Central Canal Ependymal Cells Proliferate Extensively in Response to Traumatic Spinal Cord Injury but Not Demyelinating Lesions},
  author={Steve Lacroix and Laura Kate Hamilton and Alexandre Vaugeois and St{\'e}fanny Beaudoin and Christian Breault-Dugas and Isabelle Pineau and Sebastien Levesque and Catherine-Alexandra Gr{\'e}goire and Karl J L Fernandes},
  booktitle={PloS one},
  year={2014}
}
The adult mammalian spinal cord has limited regenerative capacity in settings such as spinal cord injury (SCI) and multiple sclerosis (MS). Recent studies have revealed that ependymal cells lining the central canal possess latent neural stem cell potential, undergoing proliferation and multi-lineage differentiation following experimental SCI. To determine whether reactive ependymal cells are a realistic endogenous cell population to target in order to promote spinal cord repair, we assessed the… CONTINUE READING

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