Cellulite: a review of its physiology and treatment

@article{Avram2004CelluliteAR,
  title={Cellulite: a review of its physiology and treatment},
  author={Mathew M. Avram},
  journal={Journal of Cosmetic and Laser Therapy},
  year={2004},
  volume={6},
  pages={181 - 185}
}
  • M. Avram
  • Published 1 December 2004
  • Biology
  • Journal of Cosmetic and Laser Therapy
Cellulite affects 85–98% of post‐pubertal females of all races. While not a pathologic condition, it remains an issue of cosmetic concern to a great number of individuals. Despite its high prevalence, there have been few scientific investigations into the physiology of cellulite. There have only been a few dozen peer‐reviewed articles devoted to cellulite in the medical literature in the past 30 years. There is no definitive explanation for its presentation. This greatly complicates the ability… 

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...

References

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Current understanding of the etiology of cellulite and a variety of treatments, to include xanthines, herbal derivatives, heating, massage, and skin kneading, have been put forth as possibly reducing the dimpled skin appearance.

So-called cellulite.

Clinically the condition is characterized by “orange-peel” skin (enlarged and hyperkeratotic follicular orifices) and the “mattress” phenomenon (flattish protrusions and linear depressions of the skin surface).

Cellulite: from standing fat herniation to hypodermal stretch marks.

Histologic aspects reminiscent of stretch marks are identified within the hypodermal strands, resulting in clinical skin dimpling.

An exploratory investigation of the morphology and biochemistry of cellulite.

There is no evidence of any primary role for adipose tissue physiology, blood flow, or biochemistry in the etiology of cellulite, although the connective tissue of the female thigh is structured to accentuate differences in small subdermal adipose tissues depots.

Cellulite treatment: a myth or reality: a prospective randomized, controlled trial of two therapies, endermologie and aminophylline cream.

The best subjective assessment, by the patients themselves, revealed that only 3 of 35 aminophylline-treated legs and 10 of 35 Endermologie-treated Legs had their cellulite appearance improved.

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The clinical, epidemiological, histopathological and therapeutic aspects of cellulite are reviewed in a bid to clarify and clarify the scientific basis of this condition.

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It is hypothesized that the functional and phenotypic changes seen in this study were linked and represent the result of a direct or indirect modulating effect of retinol on cellulite, which ultimately improve the resting tensions inside the skin which should in turn smooth the skin surface.

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The purpose of this study is to establish the effectiveness of a skin massage treatment by quantifying the changes in the skin via ultrasound imaging, during and following treatment.

Topical retinol improves cellulite

A group of 20 women with moderate cellulite of the thighs were treated twice daily on one side for 6 months with a 0.3% stabilized retinol cream while the opposite side was treated with the vehicle,