Cellular versus humoral immunology: a century-long dispute
@article{Silverstein2003CellularVH, title={Cellular versus humoral immunology: a century-long dispute}, author={A. Silverstein}, journal={Nature Immunology}, year={2003}, volume={4}, pages={425-428} }
Historical insight: Immunology's founding fathers argued fiercely about whether Metchnikoff's phagocytes or Ehrlich's antibodies were the most important mediators of immunity. Antibodies won out, but even after lymphocytes re-established cellular immunology, the humoralist-cellularist divide persisted.
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References
SHOWING 1-10 OF 48 REFERENCES
Whatever happened to cell-bound antibodies? On the overriding influence of dogma
- Medicine
- Nature Immunology
- 2002
- 7
The immune system evolved to discriminate infectious nonself from noninfectious self.
- Biology, Medicine
- Immunology today
- 1992
- 1,323
Homograft Target Cells: Specific Destruction in vitro by Contact Interaction with Immune Macrophages
- Biology, Medicine
- Science
- 1964
- 157
- PDF
Mechanism of a Reaction in Vitro Associated with Delayed-Type Hypersensitivity
- Biology, Medicine
- Science
- 1966
- 1,453
The dynamics of conceptual change in twentieth century immunology.
- Biology, Medicine
- Cellular immunology
- 1991
- 36