Cellular uptake mechanism and intracellular fate of hydrophobically modified pullulan nanoparticles

@inproceedings{Jiang2013CellularUM,
  title={Cellular uptake mechanism and intracellular fate of hydrophobically modified pullulan nanoparticles},
  author={Liqin Jiang and Xuemin Li and Lingrong Liu and Qi-qing Zhang},
  booktitle={International journal of nanomedicine},
  year={2013}
}
The cellular uptake mechanism and intracellular fate of self-assembled nanoparticles (NPs) of cholesterol-modified pullulan (CHSP) by human hepatocellular carcinoma (HepG2) cells were investigated. Covalent conjugation with fluorescein isothiocyanate (FITC) yielded stably labeled CHSP (FITC-CHSP), which was successfully formulated into NPs (mean particle size 63.0 ± 1.9 nm) by dialysis. A cytotoxicity assay clearly indicated that the CHSP NPs did not show significant toxicity in HepG2 cells… CONTINUE READING
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Self-aggregated nanoparticles of cholesterol-modified pullulan conjugate as a novel carrier of mitoxantronep

  • WZ Yang, HL Chen, FP Gao
  • Curr Nanosci
  • 2010
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