Cellular uptake and anticancer activity of carboxylated gallium corroles.

@article{Pribisko2016CellularUA,
  title={Cellular uptake and anticancer activity of carboxylated gallium corroles.},
  author={Melanie A Pribisko and Joshua H. Palmer and Robert H Grubbs and Harry B. Gray and John S Termini and Punnajit P Lim},
  journal={The Journal of urology},
  year={2016},
  volume={196 5},
  pages={1584-1585}
}
We report derivatives of gallium(III) tris(pentafluorophenyl)corrole, 1 [Ga(tpfc)], with either sulfonic (2) or carboxylic acids (3, 4) as macrocyclic ring substituents: the aminocaproate derivative, 3 [Ga(ACtpfc)], demonstrated high cytotoxic activity against all NCI60 cell lines derived from nine tumor types and confirmed very high toxicity against… CONTINUE READING