Cellular transport of L-histidine in Hartnup disease.

  title={Cellular transport of L-histidine in Hartnup disease.},
  author={Sverre Halvorsen and O Hygstedt and Rudolf Jagenburg and Ottar Sjaastad},
  journal={The Journal of clinical investigation},
  volume={48 8},
The urinary excretion, the intestinal absorption, and the elimination of histidine from blood were studied in two patients with Hartnup disease. On standard diet the patients lost a great proportion of the dietary histidine in the urine, whereas the fecal loss was negligible. A high oral dose of L-histidine gave only a slight increase in plasma histidine and no increase in fecal histidine, but a considerable increase in the urinary histidine output. Intravenously administered L-histidine was… CONTINUE READING
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