Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes.

Abstract

Although a number of transfection experiments have suggested potential targets for the action of the E2F1 transcription factor, as is the case for many transcriptional regulatory proteins, the actual targets in their normal chromosomal environment have not been demonstrated. We have made use of a recombinant adenovirus containing the E2F1 cDNA to infect… (More)

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