Cellular subsets and epithelial ICAM-1 and HLA-DR expression in human papillomavirus infection of the vulva.

@article{Morelli1994CellularSA,
  title={Cellular subsets and epithelial ICAM-1 and HLA-DR expression in human papillomavirus infection of the vulva.},
  author={Adrian E Morelli and G Belardi and Giuseppe Dipaola and Alfonso Paredes and Leonardo Fainboim},
  journal={Acta dermato-venereologica},
  year={1994},
  volume={74 1},
  pages={45-50}
}
Cryostat sections of 20 clinical condylomata of the vulva induced by human papillomavirus and 5 normal control biopsies were examined using immunohistochemistry. The results indicated that in vulvar papillomavirus infection the intraepithelial Langerhans' cells showed abnormal morphology and a significantly lower density than controls. CD1a positive Langerhans' cells were also observed in dermis of condylomata, suggesting an abnormal epithelial traffic of dendritic cells. T lymphocytes with a… CONTINUE READING

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