Cellular sources of MMP-7, MMP-13 and MMP-28 in ulcerative colitis.

Abstract

OBJECTIVE Matrix metalloproteinases (MMPs) are considered the predominant proteases in the pathogenesis of mucosal ulcerations associated with inflammatory bowel disease (IBD). Whether the malignancy associated MMP-7 and MMP-13 or the recently cloned MMP-28 convey a certain meaning for intestinal homeostasis and pathogenesis of IBD is currently unknown. We… (More)
DOI: 10.3109/00365521.2010.499961

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