Cellular sensitivity to collagen in thromboangiitis obliterans.

@article{Adar1983CellularST,
  title={Cellular sensitivity to collagen in thromboangiitis obliterans.},
  author={Raphael Adar and Moshe Zvi Papa and Zamir Halpern and Marta Mozes and Shmuel Shoshan and B Sofer and Heidy Zinger and M. Kh. Dayan and Edna Mozes},
  journal={The New England journal of medicine},
  year={1983},
  volume={308 19},
  pages={1113-6}
}
We studied 39 patients with thromboangiitis obliterans to determine their cellular and humoral immune responses to native human collagen Type I and Type III, which are constituents of blood vessels. Cell-mediated sensitivity to these collagens was measured by an antigen-sensitive thymidine-incorporation assay. The mean stimulation index--the ratio of thymidine incorporation in the presence of antigen to that in its absence--with both Type I and Type III collagens used as antigens was… CONTINUE READING

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