Cellular senescence: when bad things happen to good cells

@article{Campisi2007CellularSW,
  title={Cellular senescence: when bad things happen to good cells},
  author={J. Campisi and F. D. D. Fagagna},
  journal={Nature Reviews Molecular Cell Biology},
  year={2007},
  volume={8},
  pages={729-740}
}
  • J. Campisi, F. D. D. Fagagna
  • Published 2007
  • Medicine, Biology
  • Nature Reviews Molecular Cell Biology
  • Cells continually experience stress and damage from exogenous and endogenous sources, and their responses range from complete recovery to cell death. Proliferating cells can initiate an additional response by adopting a state of permanent cell-cycle arrest that is termed cellular senescence. Understanding the causes and consequences of cellular senescence has provided novel insights into how cells react to stress, especially genotoxic stress, and how this cellular response can affect complex… CONTINUE READING

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