Cellular senescence, ageing and disease

@article{Burton2008CellularSA,
  title={Cellular senescence, ageing and disease},
  author={Dominick G A Burton},
  journal={AGE},
  year={2008},
  volume={31},
  pages={1-9}
}
Cellular senescence is the irreversible growth arrest of individual mitotic cells, which as a consequence display a radically altered phenotype that is thought to impair tissue function and predispose tissues to disease development and/or progression as they gradually accumulate. However, in the past, research into mechanisms of ageing has commonly been researched and treated separately from disease development. This may partly be due to the lack of understanding concerning mechanisms of ageing… CONTINUE READING

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