Cellular retinol-binding protein-1 expression in normal and fibrotic/cirrhotic human liver: different patterns of expression in hepatic stellate cells and (myo)fibroblast subpopulations.

@article{Lepreux2004CellularRP,
  title={Cellular retinol-binding protein-1 expression in normal and fibrotic/cirrhotic human liver: different patterns of expression in hepatic stellate cells and (myo)fibroblast subpopulations.},
  author={S{\'e}bastien Lepreux and Paulette Bioulac-Sage and Giulio Gabbiani and Vincent Sapin and Chantal Housset and Jean Rosenbaum and Charles Balabaud and Alexis Desmouli{\`e}re},
  journal={Journal of hepatology},
  year={2004},
  volume={40 5},
  pages={774-80}
}
BACKGROUND/AIMS Cellular retinol-binding protein-1 (CRBP-1) which is involved in vitamin A metabolism is highly expressed in liver cells, particularly in hepatic stellate cells (HSCs). In this work, the CRBP-1 expression was studied by immunohistochemistry in the different liver cell populations, including HSCs and portal fibroblasts, of normal liver and of fibrotic and cirrhotic liver. METHODS Normal liver, fibrotic liver in different stages and cirrhotic liver sections were studied… CONTINUE READING