Cellular responses to excess fatty acids: focus on ubiquitin regulatory X domain-containing protein 8.

Abstract

PURPOSE OF REVIEW Although fatty acids are crucial for cell survival, their overaccumulation triggers lipotoxicity that leads to metabolic syndrome. Thus, cells maintain their homeostasis by multiple feedback regulatory systems. This review focuses on how cells regulate the level of fatty acids by these systems. RECENT FINDINGS Ubiquitin regulatory X… (More)
DOI: 10.1097/MOL.0000000000000048

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