Cellular response to modulated radiation fields.

@article{Mackonis2007CellularRT,
  title={Cellular response to modulated radiation fields.},
  author={Elizabeth Claridge Mackonis and Natalka Suchowerska and Mutian Zhang and Martin A. Ebert and David R. McKenzie and Michael Jackson},
  journal={Physics in medicine and biology},
  year={2007},
  volume={52 18},
  pages={5469-82}
}
Cell survival following exposure to spatially modulated beams, as created by intensity-modulated radiotherapy (IMRT), is investigated. In vitro experiments were performed using malignant melanoma cells (MM576) exposed to a therapeutic megavoltage photon beam. We compared cell survival in modulated fields with cell survival in uniform control fields. Three different spatial modulations of the field were used: a control 'uniform' field in which all cells in a flask were uniformly exposed; a… CONTINUE READING

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