Cellular receptors of extracellular matrix molecules.

  title={Cellular receptors of extracellular matrix molecules.},
  author={Jyrki Heino and Jarmo K{\"a}pyl{\"a}},
  journal={Current pharmaceutical design},
  volume={15 12},
Extracellular matrix (ECM) is composed of large collagen fibrils. Glycoproteins, such as fibronectin, can bind to collagen or form their own networks. Collagen fibrils are also decorated by proteoglycans, proteins that have large glycosaminoglycan sidechains. In addition, extracellular space often contains hyaluronan, a large glycosaminoglycan molecule that has no core protein. Basement membranes represent a specialized form of extracellular matrix. Basement membranes are built by laminin and… CONTINUE READING


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