Cellular prostatic acid phosphatase: a protein tyrosine phosphatase involved in androgen-independent proliferation of prostate cancer.

@article{Veeramani2005CellularPA,
  title={Cellular prostatic acid phosphatase: a protein tyrosine phosphatase involved in androgen-independent proliferation of prostate cancer.},
  author={Suresh Veeramani and Ta-Chun Yuan and S C Chen and Fen-Fen Lin and Juliette E Petersen and Syed Shaheduzzaman and Shiv Srivastava and Richard G Macdonald and M Lin},
  journal={Endocrine-related cancer},
  year={2005},
  volume={12 4},
  pages={805-22}
}
Human prostatic acid phosphatase (PAcP) was used as a valuable surrogate marker for monitoring prostate cancer prior to the availability of prostate-specific antigen (PSA). Even though the level of PAcP is increased in the circulation of prostate cancer patients, its intracellular level and activity are greatly diminished in prostate cancer cells. Recent advances in understanding the function of the cellular form of PAcP (cPAcP) have shed some light on its role in prostate carcinogenesis, which… CONTINUE READING