Cellular prostatic acid phosphatase, a PTEN-functional homologue in prostate epithelia, functions as a prostate-specific tumor suppressor.

@article{Muniyan2014CellularPA,
  title={Cellular prostatic acid phosphatase, a PTEN-functional homologue in prostate epithelia, functions as a prostate-specific tumor suppressor.},
  author={Sakthivel Muniyan and Matthew A. Ingersoll and Surinder Batra and M F Lin},
  journal={Biochimica et biophysica acta},
  year={2014},
  volume={1846 1},
  pages={88-98}
}
The inactivation of tumor suppressor genes (TSGs) plays a vital role in the progression of human cancers. Nevertheless, those ubiquitous TSGs have been shown with limited roles in various stages of diverse carcinogenesis. Investigation on identifying unique TSG, especially for early stage of carcinogenesis, is imperative. As such, the search for organ-specific TSGs has emerged as a major strategy in cancer research. Prostate cancer (PCa) has the highest incidence in solid tumors in US males… CONTINUE READING
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Newton, Pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP): a new player in cell signaling

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