Cellular phosphatases facilitate combinatorial processing of receptor-activated signals

Abstract

Although reciprocal regulation of protein phosphorylation represents a key aspect of signal transduction, a larger perspective on how these various interactions integrate to contribute towards signal processing is presently unclear. For example, a key unanswered question is that of how phosphatase-mediated regulation of phosphorylation at the individual… (More)
DOI: 10.1186/1756-0500-1-81

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