Cellular origin of microparticles exposing tissue factor in cancer: a mixed double?

  • Rienk Nieuwland
  • Published 2008 in Journal of thrombosis and haemostasis : JTH


In 1995, Kakkar and coworkers showed that there is a strong association between malignant disease, circulating tissue factor (TF) and extrinsic coagulation activation. Patients suffering from malignant diseases such as gastrointestinal or gynecological cancers were shown to have, compared with healthy controls, elevated plasma concentrations of non-cell… (More)
DOI: 10.1111/j.1538-7836.2008.03069.x


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