Cellular oncogenes and lymphocyte activation.

  title={Cellular oncogenes and lymphocyte activation.},
  author={J{\"u}rgen Schneider-Schaulies and Roland Knauer and Anneliese Schimpl and Eberhard Wecker},
  journal={Behring Institute Mitteilungen},
In normal mouse splenic B and T cells at least two cellular proto-oncogenes are expressed, i.e. c-myc and c-fos. The expression of c-myc depends on the activation of the cells, but not on subsequent growth. C-fos gene expression appears to be induced by the manipulation involved in preparation of single cell suspensions from spleens. In that respect, c-fos… CONTINUE READING