Cellular models to investigate biochemical pathways in Parkinson’s disease

  title={Cellular models to investigate biochemical pathways in Parkinson’s disease},
  author={Tiziana Alberio and Leonardo Lopiano and Mauro Fasano},
  journal={The FEBS Journal},
Cellular models are instrumental in dissecting a complex pathological process into simpler molecular events. Parkinson’s disease is multifactorial and clinically heterogeneous; the aetiology of the sporadic (and most common) form is still unclear and only a few molecular mechanisms have been clarified so far in the neurodegenerative cascade. In such a multifaceted picture, it is particularly important to identify experimental models that simplify the study of the different networks of proteins… 

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  • K. Jellinger
  • Biology, Psychology
    Journal of neurochemistry
  • 2012
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