Cellular mechanisms underlying the pharmacological induction of phosphenes.

  title={Cellular mechanisms underlying the pharmacological induction of phosphenes.},
  author={Luigi Cervetto and Gian Carlo Demontis and Claudia Gargini},
  journal={British journal of pharmacology},
  volume={150 4},
Visual sensations evoked by stimuli other than luminance changes are called phosphenes. Phosphenes may be an early symptom in a variety of diseases of the retina or of the visual pathways, but healthy individuals may perceive them as well. Phosphene-like phenomena are perhaps the most common side effect reported in clinical pharmacology. Ivabradine, a novel anti-anginal drug that reduces heart-rate by inhibiting the hyperpolarization activated current expressed in cardiac sinoatrial node cells… CONTINUE READING