Cellular mechanisms of genetically controlled host resistance to Mycobacterium bovis (BCG).

@article{Gros1983CellularMO,
  title={Cellular mechanisms of genetically controlled host resistance to Mycobacterium bovis (BCG).},
  author={Philippe Gros and Emil Skamene and Adrien Forget},
  journal={Journal of immunology},
  year={1983},
  volume={131 4},
  pages={1966-72}
}
Multiplication of Mycobacterium bovis (BCG) in the reticuloendothelial tissues of the mouse is controlled by the Chromosome 1 locus (Bcg), which exists in two allelic forms, resistant (Bcgr) and susceptible (Bcgs). We have investigated the phenotypic expression of this locus at the cellular level in vivo. No significant differences were observed in the early clearance of BCG from the bloodstream and peritoneal cavity, nor in the uptake of the infectious inoculum in spleen and liver of the mice… CONTINUE READING