Cellular mechanisms of cadmium toxicity related to the homeostasis of essential metals

@article{Moulis2010CellularMO,
  title={Cellular mechanisms of cadmium toxicity related to the homeostasis of essential metals},
  author={J L Moulis},
  journal={BioMetals},
  year={2010},
  volume={23},
  pages={877-896}
}
The widespread occurrence of cadmium in the environment continues to pose a threat to human health despite attempts at limiting its technological uses. The biologically significant ionic form of cadmium, Cd2+, binds to many bio-molecules and these interactions underlie the toxicity mechanisms of cadmium. Some of the molecules specialized in the handling of alkaline earth (Mg2+, Ca2+) and transition metal ions (e.g. Zn2+, Cu2+/+, Fe3+/2+) should be particularly sensitive to the presence of Cd2… CONTINUE READING
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