Cellular mechanisms of IL-17-induced blood-brain barrier disruption.

@article{Huppert2010CellularMO,
  title={Cellular mechanisms of IL-17-induced blood-brain barrier disruption.},
  author={Jula Huppert and Dorothea Closhen and Andrew L Croxford and Robin White and Paulina Kulig and Eweline Pietrowski and Ingo Bechmann and Burkhard Becher and Heiko J. Luhmann and Ari Waisman and Christoph Ruediger Wolfram Kuhlmann},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2010},
  volume={24 4},
  pages={1023-34}
}
Recently T-helper 17 (Th17) cells were demonstrated to disrupt the blood-brain barrier (BBB) by the action of IL-17A. The aim of the present study was to examine the mechanisms that underlie IL-17A-induced BBB breakdown. Barrier integrity was analyzed in the murine brain endothelial cell line bEnd.3 by measuring the electrical resistance values using electrical call impedance sensing technology. Furthermore, in-cell Western blots, fluorescence imaging, and monocyte adhesion and transendothelial… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
93 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 93 extracted citations

Similar Papers

Loading similar papers…