Cellular localization and trafficking of the human ABCA1 transporter.

@article{Neufeld2001CellularLA,
  title={Cellular localization and trafficking of the human ABCA1 transporter.},
  author={Edward B. Neufeld and Alan T Remaley and Steve J. Demosky and John A. Stonik and Adele M. Cooney and Marcy Comly and Nancy K. Dwyer and Min Zhang and Joan E. Blanchette-Mackie and Silvia Santamarina-Fojo and Hollis B Brewer},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 29},
  pages={
          27584-90
        }
}
ABCA1, the ATP-binding cassette protein mutated in Tangier disease, mediates the efflux of excess cellular sterol to apoA-I and thereby the formation of high density lipoprotein. The intracellular localization and trafficking of ABCA1 was examined in stably and transiently transfected HeLa cells expressing a functional human ABCA1-green fluorescent protein (GFP) fusion protein. The fluorescent chimeric ABCA1 transporter was found to reside on the cell surface and on intracellular vesicles that… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 106 CITATIONS

FILTER CITATIONS BY YEAR

2002
2018

CITATION STATISTICS

  • 5 Highly Influenced Citations

  • Averaged 4 Citations per year over the last 3 years

Similar Papers

Loading similar papers…