Cellular localisation of atrial natriuretic factor in the human kidney.

@article{Figueroa1990CellularLO,
  title={Cellular localisation of atrial natriuretic factor in the human kidney.},
  author={Carlos D. Figueroa and H. M. Lewis and Angus G Maciver and J. Campbell Mackenzie and Kanti D. Bhoola},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={1990},
  volume={5 1},
  pages={25-31}
}
We have localised atrial natriuretic factor (ANF) in the human kidney by immunocytochemistry and radioimmunoassay. ANF is specifically visualised in the distal convoluted tubule cells and the intercalated cells of the connecting tubules and collecting ducts of the human nephron. The number of immunoreactive cells and tissue values for the peptide were compared between samples from normal kidneys and biopsies obtained from hypertensive patients, in whom the tissue ANF immunoreactivity was found… CONTINUE READING