Cellular in vitro assays in the diagnosis of Hymenoptera venom allergy.

  title={Cellular in vitro assays in the diagnosis of Hymenoptera venom allergy.},
  author={Kathrin Scherer and John M. Weber and Thomas M. Jermann and Andrea Krautheim and Ebru Taş and E V Ueberschlag and Meredith Cammarata and Andreas J Bircher},
  journal={International archives of allergy and immunology},
  volume={146 2},
BACKGROUND The current diagnostic procedures of anaphylactic reactions to hymenoptera stings include intradermal tests, venom-specific IgE (sIgE) and possibly sting challenge tests. Sometimes, the culprit insect remains unidentified. The usefulness of the cellular assays CAST-ELISA and Flow-CAST in the management of hymenoptera venom allergy was investigated. METHODS 134 patients with systemic reactions after a yellow jacket wasp and/or honey bee sting and 44 healthy controls underwent skin… CONTINUE READING


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