Cellular immunotherapy for patients with metastatic colorectal carcinoma using lymph node lymphocytes localized in vivo by radiolabeled monoclonal antibody.

@article{Kim1999CellularIF,
  title={Cellular immunotherapy for patients with metastatic colorectal carcinoma using lymph node lymphocytes localized in vivo by radiolabeled monoclonal antibody.},
  author={Jonghan Kim and H S Bresler and E. W. Martin and Wayne Aldrich and M. Heffelfinger and Pierre L Triozzi},
  journal={Cancer},
  year={1999},
  volume={86 1},
  pages={22-30}
}
BACKGROUND The authors showed previously that radiolabeled monoclonal antibody (MoAb) and a hand-held, gamma-detecting probe can be used to localize tumor-reactive lymph nodes in vivo. The authors examined the feasibility, safety, and biologic effects of cellular immunotherapy using autologous cells expanded from these lymph nodes in patients with metastatic colorectal carcinoma. METHODS Tumor-reactive lymph nodes containing radiolabeled MoAb were localized and excised from 32 patients with… CONTINUE READING
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