Cellular immunity to varicella-zoster virus in patients with major depression.

  title={Cellular immunity to varicella-zoster virus in patients with major depression.},
  author={Michael R. Irwin and C. Costlow and Hilary Williams and Kamal Artin and Christina Y Chan and Dora Stinson and Myron J. Levin and Anthony R. Hayward and Michael N. Oxman},
  journal={The Journal of infectious diseases},
  volume={178 Suppl 1},
The incidence of herpes zoster increases markedly with advancing age, and this appears to be causally related to an age-dependent decline in varicella-zoster virus (VZV)-specific cellular immunity. Psychologic stress has also been linked to the occurrence of herpes zoster, but the mechanism involved has not been investigated. This study examined the relationship between major depression and VZV-specific cellular immunity by comparing VZV-specific responder cell frequency (RCF) in adults with… CONTINUE READING


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