Cellular immunity to cartilage proteoglycans: relevance to the pathogenesis of ankylosing spondylitis.

@article{Jobanputra1992CellularIT,
  title={Cellular immunity to cartilage proteoglycans: relevance to the pathogenesis of ankylosing spondylitis.},
  author={Paresh Jobanputra and Ernest H Choy and Gabrielle H. Kingsley and Jochen Sieper and A A Palacios-Boix and Dick Heineg{\aa}rd and Gabriel S. Panayi},
  journal={Annals of the rheumatic diseases},
  year={1992},
  volume={51 8},
  pages={
          959-62
        }
}
Cellular immunity to cartilage proteoglycans may be responsible for sustaining chronic inflammation in ankylosing spondylitis. This hypothesis was examined by measuring peripheral blood and synovial fluid mononuclear cell proliferation in five preparations of human cartilage proteoglycan monomer in vitro. Peripheral blood mononuclear cells from 25 patients and synovial fluid mononuclear cells from five patients were compared with those from normal and disease control subjects matched for age… CONTINUE READING

Figures and Topics from this paper.

References

Publications referenced by this paper.
SHOWING 1-10 OF 18 REFERENCES

Inter - leukin 2 responsive T cell clones from rheumatoid and normal subjects : proliferative responses to connective tissue elements

K Mikecz, T Giant, M Baron, A Poole
  • tlin Immunol Immunopathol
  • 1989

Evaluation of diagnostic criteria for ankylosing spondylitis : a proposal for modification of the New York criteria

S VanderLinden, H Valkenburg, A Cats
  • Arthritis Rheum
  • 1984