Cellular immunity to Legionella pneumophila in guinea pigs assessed by direct and indirect migration inhibition reactions in vitro.

Abstract

Spleen cell cultures from guinea pigs given legionella pneumophila vaccine in complete Freund adjuvant or as a sublethal infection were inhibited in their migration activity in vitro when incubated with specific antigen. Both direct and indirect migration inhibition assays revealed sensitization of the guinea pigs to the bacterium, with demonstrable… (More)

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@article{Friedman1983CellularIT, title={Cellular immunity to Legionella pneumophila in guinea pigs assessed by direct and indirect migration inhibition reactions in vitro.}, author={H C Hyman Friedman and R E Widen and Ilha Lee and Thomas Klein}, journal={Infection and immunity}, year={1983}, volume={41 3}, pages={1132-7} }