Cellular immune response to hepatitis B virus-encoded antigens in acute and chronic hepatitis B virus infection.

@article{Ferrari1990CellularIR,
  title={Cellular immune response to hepatitis B virus-encoded antigens in acute and chronic hepatitis B virus infection.},
  author={Carlo Ferrari and Ant{\^o}nio F.S. Penna and Antonio Bertoletti and Adri{\'a}n Valli and Anna Degli Antoni and Tiziana Giuberti and Albertina Cavalli and Marie Anne Petit and Franco Fiaccadori},
  journal={Journal of immunology},
  year={1990},
  volume={145 10},
  pages={
          3442-9
        }
}
The proliferative response of PBMC to hepatitis B virus (HBV) envelope, core, and e Ag was analyzed prospectively in 21 patients with acute self-limited HBV infection and compared with the response of patients with chronic HBV infection and different levels of HBV replication (i.e., hepatitis e Ag (HBeAg)- or anti-HBe-positive) and liver damage (i.e., chronic active hepatitis or chronic asymptomatic carriers). Our results indicate that: 1) HBV-infected subjects who develop a self-limited acute… CONTINUE READING

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