Cellular immune reactivity within the CNS

@article{Wekerle1986CellularIR,
  title={Cellular immune reactivity within the CNS},
  author={H. Wekerle and C. Linington and H. Lassmann and R. Meyermann},
  journal={Trends in Neurosciences},
  year={1986},
  volume={9},
  pages={271-277}
}
Abstract We have used autoaggressive rat T lymphocyte lines specific for defined protein components of peripheral or central myelin to study lymphocyte migration and antigen recognition within the nervous system. Our recent data suggest that the nervous system is constantly patrolled by low numbers of activated T cells. Such T cells penetrate the blood—brain barrier non-specifically and recognize ‘their' antigen within the parenchyme on the surface of Ia-inducible glia cells, e.g. astrocytes or… Expand

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