Cellular fibronectins are differentially expressed in human fetal and adult kidney.

@article{Laitinen1991CellularFA,
  title={Cellular fibronectins are differentially expressed in human fetal and adult kidney.},
  author={L. Laitinen and T. Vartio and Ismo Virtanen},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  year={1991},
  volume={64 4},
  pages={492-8}
}
The localization of cellular forms of fibronectin (cFn) was studied in fetal and adult kidneys. We used monoclonal antibodies reacting with the extradomains A and B in cFN (EDAcFn, EDBcFn) as well as with a differentially glycosylated fetal form of the protein (Onc-cFn). In adult human kidney EDAcFn was present in glomerular mesangium and in the walls of larger blood vessels, whereas a polyclonal rabbit fibronectin antiserum widely reacted also with interstitial areas. Immunoreactivity for… CONTINUE READING

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