Cellular factors required for multiple stages of SV40 DNA replication in vitro.

@article{Fairman1988CellularFR,
  title={Cellular factors required for multiple stages of SV40 DNA replication in vitro.},
  author={Micaela P. Fairman and Bruce W. Stillman},
  journal={The EMBO journal},
  year={1988},
  volume={7 4},
  pages={1211-8}
}
Plasmids containing the SV40 origin replicate in the presence of SV40 T antigen and a cell free extract derived from human 293 cells. Upon fractionation of this extract, two essential replication factors have been identified. One of these is a multi-subunit DNA binding protein containing polypeptides of 70,000, 34,000 and 11,000 daltons which may function… CONTINUE READING