Cellular factors promoting resistance to effective treatment of glioma with oncolytic myxoma virus.

@article{Zemp2014CellularFP,
  title={Cellular factors promoting resistance to effective treatment of glioma with oncolytic myxoma virus.},
  author={Franz J. Zemp and Brienne A. McKenzie and Xueqing Q. Lun and Karlyne M. Reilly and Grant D McFadden and V. Wee Yong and Peter A. Forsyth},
  journal={Cancer research},
  year={2014},
  volume={74 24},
  pages={7260-73}
}
Oncolytic virus therapy is being evaluated in clinical trials for human glioma. While it is widely assumed that the immune response of the patient to the virus infection limits the utility of the therapy, investigations into the specific cell type(s) involved in this response have been performed using nonspecific pharmacologic inhibitors or allogeneic models with compromised immunity. To identify the immune cells that participate in clearing an oncolytic infection in glioma, we used flow… CONTINUE READING
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