Cellular factors modulating the mechanism of tau protein aggregation

@article{Fontaine2015CellularFM,
  title={Cellular factors modulating the mechanism of tau protein aggregation},
  author={Sarah N. Fontaine and Jonathan J. Sabbagh and Jeremy D. Baker and Carlos R. Martinez-Licha and April L. Darling and Chad A Dickey},
  journal={Cellular and Molecular Life Sciences},
  year={2015},
  volume={72},
  pages={1863-1879}
}
Pathological accumulation of the microtubule-associated protein tau, in the form of neurofibrillary tangles, is a major hallmark of Alzheimer’s disease, the most prevalent neurodegenerative condition worldwide. In addition to Alzheimer’s disease, a number of neurodegenerative diseases, called tauopathies, are characterized by the accumulation of aggregated tau in a variety of brain regions. While tau normally plays an important role in stabilizing the microtubule network of the cytoskeleton… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS
10 Citations
241 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 241 references

Similar Papers

Loading similar papers…