Cellular entry of polyomaviruses.

@article{Tsai2010CellularEO,
  title={Cellular entry of polyomaviruses.},
  author={Billy Tsai and Mengding Qian},
  journal={Current topics in microbiology and immunology},
  year={2010},
  volume={343},
  pages={177-94}
}
Polyomaviruses (Pys) are nonenveloped DNA tumor viruses that include the murine polyomavirus (mPy), simian virus 40 (SV40), and the human BK, JC, KI, WU, and Merkel Cell viruses. To cause infection, Pys must enter host cells and navigate through various intracellular compartments, where they undergo sequential conformational changes enabling them to uncoat and deliver the DNA genome into the nucleus. The ensuing transcription and replication of the genome leads to lytic infection or cell… CONTINUE READING
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