Cellular engineering: molecular repair of membranes to rescue cells of the damaged nervous system.

@article{Borgens2001CellularEM,
  title={Cellular engineering: molecular repair of membranes to rescue cells of the damaged nervous system.},
  author={Richard Ben Borgens},
  journal={Neurosurgery},
  year={2001},
  volume={49 2},
  pages={370-8; discussion 378-9}
}
PURPOSE The acute administration of hydrophilic polymers (polyethylene glycol) can immediately seal nerve membranes, preventing their continuing dissolution and secondary axotomy. Polymer application can even be used to reconnect, or fuse, the proximal and distal segments of severed axons in completely transected adult mammalian spinal cord. CONCEPT The sealing or fusion of damaged nerve membranes leads to a very rapid (minutes or hours) recovery of excitability in severely damaged nerve… CONTINUE READING

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