Cellular dynamics of tRNAs and their genes.

  title={Cellular dynamics of tRNAs and their genes.},
  author={Anita K Hopper and Dave A. Pai and David Engelke},
  journal={FEBS letters},
  volume={584 2},
This discussion focuses on the cellular dynamics of tRNA transcription, processing, and turnover. Early tRNA biosynthesis steps are shared among most tRNAs, while later ones are often individualized for specific tRNAs. In yeast, tRNA transcription and early processing occur coordinately in the nucleolus, requiring topological arrangement of approximately 300 tRNA genes and early processing enzymes to this site; later processing events occur in the nucleoplasm or cytoplasm. tRNA nuclear export… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Explore Further: Topics Discussed in This Paper


Publications citing this paper.
Showing 1-10 of 36 extracted citations

Regulatory RNAs derived from transfer RNA?

RNA • 2010
View 4 Excerpts
Highly Influenced

Regulation of tRNA gene transcription by the chromatin structure and nucleosome dynamics.

Biochimica et biophysica acta. Gene regulatory mechanisms • 2018
View 1 Excerpt

The central role of tRNA in genetic code expansion.

Biochimica et biophysica acta. General subjects • 2017
View 1 Excerpt

Apicomplexa-specific tRip facilitates import of exogenous tRNAs into malaria parasites.

Proceedings of the National Academy of Sciences of the United States of America • 2016


Publications referenced by this paper.
Showing 1-10 of 94 references

Stressing Out over tRNA Cleavage

View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…