Cellular death linked to irreversible stress in the sarcoplasmic reticulum: the effect of inhibiting Ca(2+) -ATPase or protein glycosylation in the myocardiac cell model H9c2.

@article{Soler2007CellularDL,
  title={Cellular death linked to irreversible stress in the sarcoplasmic reticulum: the effect of inhibiting Ca(2+) -ATPase or protein glycosylation in the myocardiac cell model H9c2.},
  author={Fernando Soler and Antonio Lax and Francisco Fern{\'a}ndez-Belda},
  journal={Archives of biochemistry and biophysics},
  year={2007},
  volume={466 2},
  pages={194-202}
}
Experimental sarcoplasmic reticulum damage induced by 3 microM thapsigargin or 1 microg/ml tunicamycin provoked viability loss of the cell population in approximately 72 h. Release of cytochrome c from mitochondria was an early event and Bax translocation to the mitochondria preceded or was simultaneous with cytochrome c release. The release of cytochrome c… CONTINUE READING